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PRDM10 polyclonal antibody（KU）

货号: BS60764

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60764

Product Name :PRDM10 polyclonal antibody（KU）

Swiss-Prot :Q9NQV6

Host :Rabbit

Reactivity :Human,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The PR-domain containing proteins (PRDMs) have a common involvement in the modulation of gene activities. A PR-domain family member usually produces two products, which differ by the presence or absence of the PR domain. The PR-plus product is underexpressed or disrupted, whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, which is a result of either genetic or epigenetic events, appears to be a determining cause of malignancy. PRDM10 (PR domain containing 10), also known as PFM7 or TRIS, is a 1,147 amino acid protein that contains ten C2H2-type zinc fingers and one SET domain. Existing as six alternatively spliced isoforms, PRDM10 localizes nucleus and may be involved in transcriptional regulation. PRDM10 may also play a role in the development of the central nerve system, as well as in the pathogenesis of neuronal storage disease.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PRDM10 polyclonal antibody detects endogenous levels of PRDM10 protein.

BiowMW :~ 130 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PR domain zinc finger protein 10; PR domain-containing protein 10; Tristanin; PRDM10; KIAA1231; PFM7; TRIS

Immunogen :A synthetic peptide corresponding to residues in Human PRDM10

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of PRDM10 pAb at 1:500 dilution Lane1:The Testis tissue lysate of Rat(40ug) Lane2:A375 whole cell lysate(40ug) Lane3:A2780 whole cell lysate(40ug) Lane4:SGC7901 whole cell lysate(40ug)