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ITGA2B polyclonal antibody

货号: BS60754

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60754

Product Name :ITGA2B polyclonal antibody

Swiss-Prot :P08514

Host :Rabbit

Reactivity :Human,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16 α and 8 β subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.β

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ITGA2B polyclonal antibody detects endogenous levels of ITGA2B protein.

BiowMW :~ 113 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Contribution of ECM and Cytoskeletal Factors to EMT,

Alternative Name :Integrin alpha-Iib; GPalpha Iib; GPIIb; Platelet membrane glycoprotein Iib; CD41; ITGA2B; GP2B; ITGAB

Immunogen :A synthetic peptide corresponding to residues in Human ITGA2B

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ITGA2B polyclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate Lane2:MCF-7 whole cell lysate Lane3:PC12 whole cell lysate