Product Name :INTS2 polyclonal antibody
Application_all :IHC: 1:50~1:200
Background :Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267).
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :INTS2 polyclonal antibody detects endogenous levels of INTS2 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Integrator complex subunit 2; Int2; INTS2; KIAA1287
Immunogen :Synthetic peptide, corresponding to amino acids 50-100 of Human INTS2.
Modification :Unmodification