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TRAF3IP1 polyclonal antibody

货号: BS60709

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS60709

Product Name :TRAF3IP1 polyclonal antibody

Swiss-Prot :Q8TDR0

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Tumor necrosis factor receptor (TNFR) superfamily members transmit signals regulating proliferation, differentiation and apoptosis in various types of cells . TNFR-associated factors (TRAFs) are a family of proteins that were initially discovered as downstream signal transducers of the TNFR superfamily. TRAF3 contains an N-terminal ring finger/zinc finger region that is thought to be essential for downstream signaling . MIP-T3 is associated with TRAF3. MIP-T3 binds to taxol-stabilized microtubules and to tubulin in vitro, and MIP-T3 recruits TRAF3 to microtubules when both proteins are overexpressed. The MIP-T3/TRAF3 interaction requires the coiled-coil TRAF-N domain of TRAF3 . This interaction may provide a novel mechanism in sequestering TRAF3 to the cytoskeletal network.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TRAF3IP1 polyclonal antibody detects endogenous levels of TRAF3IP1 protein.

BiowMW :~ 79 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TRAF3-interacting protein 1; Interleukin-13 receptor alpha 1-binding protein 1; Intraflagellar transport protein 54 homolog; Microtubule-interacting protein associated with TRAF3; MIP-T3; TRAF3IP1; IFT54; MIPT3

Immunogen :A synthetic peptide corresponding to residues in Human TRAF3IP1

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of TRAF3IP1 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate