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KIRREL2 polyclonal antibody

货号: BS60707

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60707

Product Name :KIRREL2 polyclonal antibody

Swiss-Prot :Q6UWL6

Host :Rabbit

Reactivity :Human,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :NEPH3 (nephrin-like protein 3), also referred to as NLG1, FILTRIN or KIRREL2 (kin of IRRE like 2), is a 708 amino acid protein that is a member of the immunoglobulin superfamily of cell adhesion molecules. NEPH3 consists of five extracellular Ig-like repeats, a transmembrane domain, several glycosylation sites and a cytoplasmic domain that has a stretch of nine conserved residues. NEPH3 localizes to the interpodocyte filtration slit in the kidney and to the Langerhans islet beta cells in the pancreas. NEPH3 is thought to be involved in the maintenance of the glomerular filtration barrier in the kidney and in pancreas development. Downregulation of NEPH3 is implicated in several proteinuric diseases. Five isoforms exists due to alternative splicing events.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :KIRREL2 polyclonal antibody detects endogenous levels of KIRREL2 protein.

BiowMW :~ 75 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Kin of IRRE-like protein 2; Kin of irregular chiasm-like protein 2; Nephrin-like protein 3; KIRREL2NEPH3; UNQ5827; PRO19646

Immunogen :A synthetic peptide corresponding to residues in Human KIRREL2

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of KIRREL2 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:H9C2 whole cell lysate

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）