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MMP21 polyclonal antibody

货号: BS60692

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60692

Product Name :MMP21 polyclonal antibody

Swiss-Prot :Q8N119

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The matrix metalloproteinases (MMPs) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-21 is 569 amino acid residues in length and consists of a prodomain, catalytic domain, and haemopexin-like domain. It is the human orthologue for XMMP in X. laevis and CyMMP in C. pyrrhogaster. MMP-21 is expressed in various fetal and adult tissues. It a possible target gene of the Wnt pathway, and the expression of this protein is controlled by Pax and Notch transcription factors. MMP-21 may play an important role in embryogenesis, tissue development (particularly in the brain), tumor progression and possibly apoptosis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MMP21 polyclonal antibody detects endogenous levels of MMP21 protein.

BiowMW :~ 65 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Matrix metalloproteinase-21; MMP-21

Immunogen :A synthetic peptide corresponding to residues in Human MMP21

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of MMP21 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）