产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

IL-1β polyclonal antibody

货号: BS6067

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6067

Product Name :IL-1β polyclonal antibody

Swiss-Prot :P01584

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB 1:500 - 1:1000 IHC 1:100 - 1:200

Background :Two forms of interleukin-1, designated IL-1α and IL-1β, have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity, IL-1α and IL-1β bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation, but it has also been shown to be expressed during kidney development, thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation, acting as an activator of T and B lymphocytes and natural killer (NK) cells.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IL-1β polyclonal antibody detects endogenous levels of IL-1β protein.

BiowMW :~ 31, 17 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Immune Cell Signaling,Inflammasonme Signaling,Necrotic Cell Death,

Alternative Name :Interleukin-1 beta; IL-1 beta; Catabolin; IL1B; IL1F2; IL-1β; IL1β

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IL-1 beta.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of IL-1 beta expression in Raw264.7 (A), mouse spleen (B), rat spleen (C), rat thymus (D), mouse thymus (E), Jurkat (F), THP1 (G) whole cell lysates.

Immunohistochemical analysis of IL-1 beta staining in human lung cancer formalin fixed paraffin embedded tissue section.

AICAR, an AMP-Activated Protein Kinase Activator, Ameliorates Acute Pancreatitis-Associated Liver Injury Partially Through Nrf2-Mediated Antioxidant Effects and Inhibition of NLRP3 Inflammasome Activation

JournalFrontiers in Pharmacology

ApplicationIHC

IF5.81

SpeciesRat

PMID34531748
PTEN Methylation Promotes Inflammation and Activation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis

JournalFrontiers in Pharmacology

ApplicationWB

IF5.81

SpeciesHuman

PMID34305608
Glucagon-Like Peptide-1 Analog Exendin-4 Ameliorates Cocaine-Mediated Behavior by Inhibiting Toll-Like Receptor 4 Signaling in Mice

JournalFrontiers in Pharmacology

ApplicationWB

IF5.81

SpeciesMouse

PMID34349653
7-Hydroxycoumarin mitigates the severity of collagen-induced arthritis in rats by inhibiting proliferation and inducing apoptosis of fibroblast-like synoviocytes via suppression of Wnt/β-catenin signaling pathway

JournalPhytomedicine

ApplicationWB

IF5.34

SpeciesRat

PMID34752968
Low‐intensity pulsed ultrasound attenuates cardiac inflammation of CVB3‐induced viral myocarditis via regulation of caveolin‐1 and MAPK pathways

JournalJournal Of Cellular And Molecular Medicine

ApplicationWB

IF4.658

SpeciesMouse

PMID30592150