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CTSL1 polyclonal antibody

货号: BS60598

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60598

Product Name :CTSL1 polyclonal antibody

Swiss-Prot :P07711

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin L (also designated major excreted protein, MEP or CATL) is a member of the peptidase C1 family and has been identified as a protein that is most closely related to cathepsin H. It is a lysosomal cysteine proteinase that mediates intracellular protein catabolism for collagen, elastin and å-1 protease inhibitor. Cathepsin L is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene. Transformed mouse fibroblasts stimulated by growth factors or tumor promoters secrete a form of cathepsin L.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CTSL1 polyclonal antibody detects endogenous levels of CTSL1 protein.

BiowMW :~ 43 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cathepsin L1; Cathepsin L; Major excreted protein; MEP; CTSL; CTSL1

Immunogen :A synthetic peptide corresponding to residues in Human CTSL1

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CTSL1 pAb at 1:500 dilution Lane1:U-87MG whole cell lysate(40ug) Lane2:A549 whole cell lysate(40ug) Lane3:HepG2 whole cell lysate(40ug)

DIFFERENTIATED EMBRYONIC CHONDROCYTE EXPRESSED GENE-1 IS A CENTRAL SIGNALING COMPONENT IN THE DEVELOPMENT OF COLLAGEN-INDUCED RHEUMATOID ARTHRITIS

JournalJOURNAL OF BIOLOGICAL CHEMISTRY

ApplicationWB

IF5.486

SpeciesMouse, Human

PMID36739947
Expression, Purification and Biological Activity Evaluation of Cathepsin L in Mammalian Cells

JournalBIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

ApplicationWB

IF1.6

SpeciesHuman

PMID38271604