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UBE2U polyclonal antibody

货号: BS60597

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS60597

Product Name :UBE2U polyclonal antibody

Swiss-Prot :Q5VVX9

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires ATP-dependent activation of the Ub C-terminus and assembly of multi-Ub chains by a Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2U (ubiquitin-conjugating enzyme E2U) is a 321 amino acid E2 ubiquitin conjugating enzyme that catalyzes the covalent attachment of ubiquitin to other proteins. Existing as two alternatively spliced isoforms, UBE2U is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :UBE2U polyclonal antibody detects endogenous levels of UBE2U protein.

BiowMW :~ 38 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Ubiquitin Proteasome,

Alternative Name :Ubiquitin-conjugating enzyme E2 U; Ubiquitin carrier protein U; Ubiquitin-protein ligase U; UBE2U

Immunogen :A synthetic peptide corresponding to residues in Human UBE2U

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of UBE2U polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate

免疫沉淀（IP）

免疫组织化学（IHC）