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CTSK polyclonal antibody

货号: BS60594

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60594

Product Name :CTSK polyclonal antibody

Swiss-Prot :P43235

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O . The aspartyl protease class is composed of cathepsins D and E . Cathepsin G is in the serine protease class . Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin K expression is highest in bone, cartilage and skeletal muscle. The strongest mRNA levels are revealed in osteoclasts .

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CTSK polyclonal antibody detects endogenous levels of CTSK protein.

BiowMW :~ 43 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cathepsin K; Cathepsin O; Cathepsin O2; Cathepsin X; CTSK; CTSO; CTSO2

Immunogen :A synthetic peptide corresponding to residues in Human CTSK

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CTSK pAb at 1:500 dilution Lane1:MCF-7 whole cell lysate(40ug) Lane2:A375 whole cell lysate(40ug) Lane3:HCT116 whole cell lysate(40ug)

The protective effect of WKYMVm peptide on inflammatory osteolysis through regulating NF-κB and CD9/gp130/STAT3 signalling pathway

JournalJournal Of Cellular And Molecular Medicine

ApplicationWB

IF5.31

SpeciesMouse

PMID31837208
LncRNA AK077216 promotes RANKL‐induced osteoclastogenesis and bone resorption via NFATc1 by inhibition of NIP45

JournalJournal Of Cellular Physiology

ApplicationWB

IF4.522

SpeciesMouse

PMID30132869