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RLN3 polyclonal antibody

货号: BS60503

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60503

Product Name :RLN3 polyclonal antibody

Swiss-Prot :Q8WXF3

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Relaxin 3 is part of the Relaxin-like peptide family that plays an important neuropeptide signaling role. Relaxin 3 is a ligand for two structurally related G protein-coupled receptors, human Relaxin receptor 3 and Relaxin receptor 4. The greatest levels of Relaxin 3 expression occur in the brain, specifically in the pons/medulla, with highest levels in the pars ventromedialis of the dorsal tegmental nucleus and with lower levels in the hippocampus and olfactory regions. Significant expression is also observed in the spleen, thymus, lung and ovary. Relaxin 3 inhibits Forskolin-stimulated cAMP accumulation in a dose-dependent manner in cells that express Relaxin receptor 3. Acute and repeated administration of Relaxin 3 causes a decrease in levels of the plasma thyroid stimulating hormone, suggesting that Relaxin 3 may play a role in long-term control of food intake.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :RLN3 polyclonal antibody detects endogenous levels of RLN3 protein.

BiowMW :~ 15 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Relaxin-3; Insulin-like peptide INSL7; Insulin-like peptide 7; Prorelaxin H3; RLN3; INSL7, RXN3, ZINS4; UNQ6188; PRO20213

Immunogen :A synthetic peptide corresponding to residues in Human RLN3.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of RLN3 polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate Lane2:HEK293T whole cell lysate Lane3:Raw264.7 whole cell lysate