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PROK1 polyclonal antibody

货号: BS60468

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS60468

Product Name :PROK1 polyclonal antibody

Swiss-Prot :P58294

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) induces proliferation,migration and fenestration in capillary endothelialcells derived from endocrine glands. EG-VEGF possesses a HIF-1 binding site; its expression isinduced by hypoxia and restricted to the steroidogenic glands(ovary,testis, adrenal and placenta). EG-VEGF expression is often complementary to the expression of VEGF,suggesting that these moleculesfunction in a coordinatedmanner. EG-VEGFis an example of a class of highly specificmitogensthat act to regulate proliferation and differentiation of the vascular endothelium in a tissue-specific manner. EG-VEGFis expressed largely in one type of tissue and actsselectively on one type of endothelium. EG-VEGF, possiblythrough binding to a G protein-coupled receptor, resultsin the activation ofMAPK p44/42 and phosphatidylinositol 3-kinase signaling pathways, leading to proliferation,migration and survival of responsive endothelialcells.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PROK1 polyclonal antibody detects endogenous levels of PROK1 protein.

BiowMW :~ 12 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Prokineticin-1; Endocrine-gland-derived vascular endothelial growth factor; EG-VEGF; Mambakine; PROK1; UNQ600/PRO1186

Immunogen :A synthetic peptide corresponding to residues in Human PROK1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of PROK1 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate