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Mitofilin polyclonal antibody

货号: BS60403

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS60403

Product Name :Mitofilin polyclonal antibody

Swiss-Prot :Q16891

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Cristae are highly folded inner mitochondrial membrane compartments that are studded with cytochromes and ATP synthase proteins and function to provide a large surface area upon which cellular respiration can occur. Mitofilin, also known as IMMT, HMP, PIG4 or P87/89, is a 758 amino acid inner mitochondrial membrane protein that is preferentially expressed in heart tissue. Existing as three alternatively spliced isoforms, Mitofilin functions to control mitochondrial cristae morphology, including the formation and organization of cristae junctions and normal tubular cristae. Due to its role in mediating cristae structure and function, Mitofilin is essential for normal mitochondrial function and is, thus, critical to overall cell survival.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mitofilin polyclonal antibody detects endogenous levels of Mitofilin protein.

BiowMW :~ 84 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Mitochondrial inner membrane protein; Cell proliferation-inducing gene 4/52 protein; Mitofilin; p87/89; IMMT; HMP; MINOS2; PIG4; PIG52

Immunogen :A synthetic peptide corresponding to residues in Human Mitofilin.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Mitofilin polyclonal antibody at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:sp2/0 cell lysate Lane3:PC12 cell lysate

Regulation of mitochondrial cristae remodelling by acetylcholine alleviates palmitate-induced cardiomyocyte hypertrophy

JournalFree Radical Biology And Medicine

ApplicationIP,WB,IF

IF5.657

SpeciesRat

PMID31553938