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NPPC polyclonal antibody

货号: BS60381

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS60381

Product Name :NPPC polyclonal antibody

Swiss-Prot :P23582

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP) . ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control . ANP, BNP, and CNP are highly homologous within the 17-residue ring structure formed by an intramolecular disulfide linkage . The genes which encode for ANP and BNP map to human chromosome 1p36.2 . The gene which encodes for CNP maps to human chromosome 2q24-qter .

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NPPC polyclonal antibody detects endogenous levels of NPPC protein.

BiowMW :~ 7 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :C-type natriuretic peptide; Cleaved into the following 3 chains:CNP-22; CNP-29; CNP-53; NPPC; CNP2

Immunogen :A synthetic peptide corresponding to residues in Human NPPC.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of NPPC polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Mouse heart tissue lysate Lane3:Rat heart tissue lysate