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IL2 polyclonal antibody

货号: BS60299

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS60299

Product Name :IL2 polyclonal antibody

Swiss-Prot :P60568

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Lymphokines are a group of signaling molecules involved in communication between cells of the immune system. Lymphokines secreted by activated lymphocytes include proteins such as IL-2. This protein is secreted primarily by helper T cells that have been activated through the T cell receptor complex or by other mitogens. Cells targeted by IL-2 include activated T helper and cytotoxic T cells, inducing their proliferation. The secretion of IL-2 can also act as a growth factor for B cells. To date, three different IL-2-dependent signal transduction pathways have been identified: the c-Fos/c-Jun induction pathway mediated by Src family protein-tyrosine kinases; the c-Myc induction pathway; and the Rapamycin-sensitive pathway; all of which result in the induction of Bcl-2. In addition, the transcription factor NFAT has been shown to play a major role in the regulation of IL-2 transcription and correlates to an age-related decline in the expression of IL-2.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IL2 polyclonal antibody detects endogenous levels of IL2 protein.

BiowMW :~ 18 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Interleukin-2; IL-2; T-cell growth factor; TCGF; INN=Aldesleukin; IL2

Immunogen :A synthetic peptide corresponding to residues in Human IL2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of IL2 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:NIH-3T3 whole cell lysate Lane3:H9C2 whole cell lysate

Huangkui capsule, an extract from Abelmoschus manihot (L.) medic, ameliorates adriamycin-induced renal inflammation and glomerular injury via inhibiting p38MAPK signaling pathway activity in rats

JournalJournal Of Ethnopharmacology

ApplicationWB

IF3.69

SpeciesRat

PMID23518420