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SPAG9 polyclonal antibody

货号: BS60271

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60271

Product Name :SPAG9 polyclonal antibody

Swiss-Prot :O60271

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :JIP-4 (C-jun-amino-terminal kinase-interacting protein 4, Mitogen-activated protein kinase 8-interacting protein 4, Sunday driver 1) is a 1,321 amino acid protein encoded by the human gene SPAG9. It contains a large N-terminal extracellular domain, a short transmembrane helical domain, and a cytoplasmic domain. There are 6 N-glycosylation sites, several phosphorylation sites for cAMP/cGMP-dependent protein kinase, protein kinase C, and casein kinase II, and 10 putative myristoylation sites. There is also a leucine zipper motif, with 6 leucine repeats, that may aid in dimerization since there is no upstream basic domain characteristic of DNA binding proteins. The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP-4 is a cytoplasmic, perinuclear protein that has eight known isoforms whose expression varies by tissue and disease state.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SPAG9 polyclonal antibody detects endogenous levels of SPAG9 protein.

BiowMW :~ 146 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :C-Jun-amino-terminal kinase-interacting protein 4; JIP-4; JNK-interacting protein 4; Cancer/testis antigen 89; CT89;Human lung cancer oncogene 6 protein; HLC-6; JNK-associated leucine-zipper protein; JLP; Mitogen-activated protein kinase 8-interacting protein 4; Proliferation-inducing protein 6; Protein highly expressed in testis; PHET; Sperm surface protein; Sperm-associated antigen 9; Sperm-specific protein; Sunday driver 1; SPAG9; HSS, KIAA0516, MAPK8IP4, SYD1; HLC6

Immunogen :A synthetic peptide corresponding to residues in Human SPAG9.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of SPAG9 pAb at 1:500 dilution Lane1:AML-12 whole cell lysate(40ug) Lane2:U-87MG whole cell lysate(40ug) Lane3:EC9706 whole cell lysate(40ug) Lane4:SGC7901 whole cell lysate(40ug)