Product Name :CDC42 polyclonal antibody
Reactivity :Human,Mouse,Rat
Application_all :WB: 1:500~1:1000
Background :The superfamily of GTP-binding proteins, for which the Ras proteins are prototypes, has been implicated in regulation of diverse biological activities involving various aspects of cell growth and division. One mammalian member of the family, Cdc42, has an amino acid sequence that is similar to those of various members of the Ras superfamily proteins, including N-, K- and H-Ras, Rho proteins and the Rac proteins. On the basis of in vitro phosphorylation studies, it has been suggested that human Cdc42 may function in the signaling pathway of the EGF receptor or related growth factor receptor protein kinases. The Dbl oncogene has been shown to specifically catalyze dissociation of GDP from human Cdc42.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :CDC42 polyclonal antibody detects endogenous levels of CDC42 protein.
Note :For research use only, not for use in diagnostic procedure.
Pathway :Phosphoinosotode Signaling,SAPK JNK Signaling Cascades,SAPK JNK Signaling Cascades,Contribution of Soluble Factors to EMT,Adherens Junction signaling,
Alternative Name :Cell division control protein 42 homolog; G25K GTP-binding protein; CDC42
Immunogen :A synthetic peptide corresponding to residues in Human CDC42.
Modification :Unmodification
