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TMC7 polyclonal antibody

货号: BS60259

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS60259

Product Name :TMC7 polyclonal antibody

Swiss-Prot :Q7Z402

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :TMC7 (Transmembrane channel-like protein 7) is a 723 amino acid protein that is a member of the TMC protein family. All TMC genes encode transmembrane proteins with intracellular amino- and carboxy- termini and at least eight membrane spanning domains. Therefore, TMC7 is a multi-pass membrane protein that may regulate or function as an ion channel or transporter. The gene encoding TMC7 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TMC7 polyclonal antibody detects endogenous levels of TMC7 protein.

BiowMW :~ 84 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Transmembrane channel-like protein 7

Immunogen :A synthetic peptide corresponding to residues in Human TMC7.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of TMC7 polyclonal antibody at 1:500 dilution Lane1:THP-1 whole cell lysate Lane2:NIH-3T3 whole cell lysate Lane3:H9C2 whole cell lysate