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RAC2 polyclonal antibody

货号: BS60217

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS60217

Product Name :RAC2 polyclonal antibody

Swiss-Prot :P15153

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :A large number of low molecular weight, GTP binding proteins of the Ras superfamily have been identified. These proteins regulate many fundamental processes in all eukaryotic cells such as growth, vesicle traffic and cytoskeletal organization. GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. Two proteins in this family, Rac 1 and Rac 2, are 92% identical and share GTP binding and GTP hydrolysis motifs with other members of the Ras superfamily. Rac 1 is expressed in a large number of different cell types. Rac 2 is primarily expressed only in myeloid cells and has been reported to be a regulatory component of the human neutrophil NADPH oxidase.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :RAC2 polyclonal antibody detects endogenous levels of RAC2 protein.

BiowMW :~ 21 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :SAPK JNK Signaling Cascades,Contribution of ECM and Cytoskeletal Factors to EMT,

Alternative Name :Ras-related C3 botulinum toxin substrate 2; GX; Small G protein; p21-Rac2

Immunogen :A synthetic peptide corresponding to residues in Human RAC2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of RAC2 polyclonal antibody at 1:500 dilution Lane1:Jurkat whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:H9C2 whole cell lysate