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MT-ND2 polyclonal antibody（KU）

货号: BS60187

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60187

Product Name :MT-ND2 polyclonal antibody（KU）

Swiss-Prot :P03891

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :MT-ND2: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Defects in MT-ND2 are a cause of Leber hereditary optic neuropathy (LHON). LHON is a maternally inherited disease resulting in acute or subacute loss of central vision, due to optic nerve dysfunction. Cardiac conduction defects and neurological defects have also been described in some patients. LHON results from primary mitochondrial DNA mutations affecting the respiratory chain complexes. Defects in MT-ND2 may be associated with susceptibility to Alzheimer disease mitochondrial (AD-MT).

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MT-ND2 polyclonal antibody detects endogenous levels of MT-ND2 protein.

BiowMW :~ 39 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NADH-ubiquinone oxidoreductase chain 2; NADH dehydrogenase subunit 2; MTND2; NADH2; ND2

Immunogen :A synthetic peptide corresponding to residues in Human MT-ND2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of MT-ND2 polyclonal antibody at 1:1000 dilution Lane1:The brain tissue lysate of mouse(30ug) Lane2:The brain tissue lysate of Rat(30ug)

Ad36 promotes differentiation of hADSCs into brown adipocytes by up-regulating LncRNA ROR

JournalLife Sciences

ApplicationWB

IF3.647

SpeciesHuman

PMID33189825