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CD248 polyclonal antibody

货号: BS60152

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60152

Product Name :CD248 polyclonal antibody

Swiss-Prot :Q9HCU0

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Tumor endothelial marker 1 (TEM1/endosialin) is a heavily glycosylated, type I transmembrane C-type lectin-like receptor of the Ras superfamily expressed in the vascular endothelium and on fibroblast-like cells in developing organs. Expression of TEM1 largely disappears in adulthood. TEM1 is structurally related to thrombomodulin and complement receptor C1qRp. It consists of three EGF-like domains, a C-type lectin domain and a Sushi domain. TEM1 is highly upregulated in tumor endothelium and is known to function in tumor growth and progression. For this reason TEM1 is a major target in anti-angiogenic tumor therapy. TEM1 may be responsible for concentrating liposomes on the surface of target cells and promoting their fusion with the cell membrane.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD248 polyclonal antibody detects endogenous levels of Endosialin protein.

BiowMW :~ 50, 80 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Endosialin; Tumor endothelial marker 1; CD164L1; TEM1

Immunogen :A synthetic peptide corresponding to residues in Human CD248.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CD248 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:NIH-3T3 whole cell lysate Lane3:H9C2 whole clel lysate