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XRCC4 polyclonal antibody

货号: BS60079

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS60079

Product Name :XRCC4 polyclonal antibody

Swiss-Prot :Q13426

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad51. XRCC4 is an accessory factor of DNA ligase IV that preferentially binds DNA with nicks or broken ends. XRCC4 binds to DNA ligase IV and enhances its joining activity, and it is also involved in V(D)J recombination. Any defect in one of the known components of the DNA repair/V(D)J recombination machinery (Ku-70, Ku-80, DNA-PKCS, XRCC4 and DNA ligase IV) leads to abortion of the V(D)J rearrangement process and early block in both T and B cell maturation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :XRCC4 polyclonal antibody detects endogenous levels of XRCC4 protein.

BiowMW :~ 38 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DNA repair protein XRCC4; X-ray repair cross-complementing protein 4; XRCC4

Immunogen :A synthetic peptide corresponding to residues in Human XRCC4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of XRCC4 polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:HEK293T whole cell lysate Lane3:NIH-3T3 whole cell lysate