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Bag-3 polyclonal antibody

货号: BS60002

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS60002

Product Name :Bag-3 polyclonal antibody

Swiss-Prot :O95817

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Bag-3 (Bcl-2-associated athanogene 3), also known as BIS or CAIR-1, is a 575 amino acid protein that contains one C-terminal Bag domain and two N-terminal WW domains. Like other members of the Bag family, Bag-3 functions to inhibit the chaperone activity of HSP 70, specifically by promoting the release of HSP 70-bound substrates. Additionally, Bag-3 exhibits anti-apoptotic activity via cell cycle control, suggesting a possible role for Bag-3 in tumor progression. The gene encoding Bag-3 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Bag-3 polyclonal antibody detects endogenous levels of Bag-3 protein.

BiowMW :~ 62, 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BAG 3; BAG family molecular chaperone regulator 3; BAG-3; Bag3; BAG3; Bcl 2 binding protein; Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis; BCL2 associated athanogene 3; BCL2 binding athanogene 3; BIS; Docking protein CAIR 1; Docking protein CAIR-1;

Immunogen :A synthetic peptide corresponding to residues in Human Bag-3.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Bag-3 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate