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ZNF50 polyclonal antibody

货号: BS5985

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS5985

Product Name :ZNF50 polyclonal antibody

Swiss-Prot :P10073

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZSCAN22 (zinc finger and SCAN domain-containing protein 22), also known as HKR2 or ZNF50 (zinc finger protein 50), is a 491 amino acid nuclear protein. Belonging to the Krueppel C2 H2-type zinc-finger protein family, ZSCAN22 contains eight C2 H2-type zinc fingers and one SCAN box domain. ZSCAN22 may be involved in transcriptional regulation, and becomes phosphorylated upon DNA damage.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ZNF50 polyclonal antibody detects endogenous levels of ZNF50 protein.

BiowMW :~ 55 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Zinc finger and SCAN domain-containing protein 22; Krueppel-related zinc finger protein 2; Protein HKR2; Zinc finger protein 50; ZSCAN22; HKR2

Immunogen :Synthetic peptide, corresponding to amino acids 363-408 of Human ZNF50.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ZNF50 polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:sp2/0 cell lysate Lane3:PC12 cell lysate

Immunohistochemistry (IHC) analyzes of ZNF50 pAb in paraffin-embedded human stomach carcinoma tissue at 1:50.showing nucleus staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.