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USP19 polyclonal antibody

货号: BS5975

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS5975

Product Name :USP19 polyclonal antibody

Swiss-Prot :O94966

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. Ubiquitin-specific-processing protease 19 (USP19), also known as ubiquitin carboxyl-terminal hydrolase 19, ubiquitin thioesterase 19 and deubiquitinating enzyme 19, is a 1318 amino acid member of the peptidase C19 family of proteins. USP19 is thought to be involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome. Four known isoforms of USP19 exist as a result of alternative splicing events.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :USP19 polyclonal antibody detects endogenous levels of USP19 protein.

BiowMW :~ 146 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Ubiquitin carboxyl-terminal hydrolase 19; Deubiquitinating enzyme 19; Ubiquitin thioesterase 19; Ubiquitin-specific-processing protease 19; Zinc finger MYND domain-containing protein 9; USP19; KIAA0891; ZMYND9

Immunogen :Synthetic peptide, corresponding to amino acids 439-484 of Human USP19.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of USP19 polyclonal antibody at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:HEK293T cell lysate Lane3:H9C2 cell lysate

Immunohistochemistry (IHC) analyzes of USP19 pAb in paraffin-embedded human breast carcinoma tissue at 1:50.showing endoplasmic reticulum membrane staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.