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SSBP2 polyclonal antibody

货号: BS5946

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS5946

Product Name :SSBP2 polyclonal antibody

Swiss-Prot :P81877

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :The single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells, as well as in mitochondria, bacteria and viruses. SSBP2 (single-stranded DNA binding protein 2), also known as SSDP2, is a 361 amino acid protein that localizes to the nucleus and contains one LisH domain. Expressed ubiquitously, SSBP2 is thought to induce growth arrest in cancer cells and may, therefore, function as a potent tumor suppressor. The gene encoding SSBP2 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Defects in chromosome 5-associated genes are related to the pathogenesis of Cockayne syndrome, familial adenomatous polyposis and Treacher Collins syndrome.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SSBP2 polyclonal antibody detects endogenous levels of SSBP2 protein.

BiowMW :~ 38 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Single-stranded DNA-binding protein 2; Sequence-specific single-stranded-DNA-binding protein 2; SSBP2; SSDP2

Immunogen :Synthetic peptide, corresponding to amino acids 2-47 of Human SSBP2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of SSBP2 polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:NIH-3T3 cell lysate Lane3:Rat kidney tissue lysate

Immunohistochemistry (IHC) analyzes of SSBP2 pAb in paraffin-embedded human colon carcinoma tissue at 1:50.showing cytoplasmic and nucleus staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Immunohistochemistry (IHC) analyzes of SSBP2 pAb in paraffin-embedded human kidney carcinoma tissue at 1:50.showing cytoplasmic and nucleus staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.