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Renin Receptor polyclonal antibody

货号: BS5887

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS5887

Product Name :Renin Receptor polyclonal antibody

Swiss-Prot :O75787

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The Renin Receptor, also known as ATP6AP2 (ATPase H+-transporting lysosomal accessory protein 2), ATP6IP2 (ATPase H+-transporting lysosomal-interacting protein 2), CAPER or M8-9, is an ATPase-associated protein that functions as a Renin and prorenin cellular receptor. Expressed in the brain, heart, liver, kidney, placenta and pancreas, the Renin Receptor functions to activate ERK 1 and ERK 2, thereby mediating Renin-dependent cellular responses. The Renin Receptor has a subunit that associates with the transmembrane domain of V-type ATPases and interacts with Renin. These interactions increase the catalytic activity of Renin in the Renin-Angiotensin system (RAS), thus upregulating the conversion of angiotensinogen to Angiotensin.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Renin Receptor polyclonal antibody detects endogenous levels of Renin Receptor protein.

BiowMW :~ 43kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ATPase H(+)-transporting lysosomal accessory protein 2; ATPase H(+)-transporting lysosomal-interacting protein 2; ER-localized type I transmembrane adaptor; Embryonic liver differentiation factor 10 N14F; Renin/prorenin receptor; Vacuolar ATP synthase membrane sector-associated protein M8-9; ATP6M8-9; V-ATPase M8.9 subunit; ATP6AP2; ATP6IP2; CAPER; ELDF10; HT028; MSTP009; PSEC0072

Immunogen :Synthetic peptide, corresponding to amino acids 209-254 of Human Renin Receptor.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ATP6AP2 pAb at 1:500 dilution Lane1:THP-1 whole cell lysate(40ug) Lane2:HEK293T whole cell lysate(40ug) Lane3:Hela whole cell lysate(40ug) Lane4:CT-26 whole cell lysate(40ug)