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Radixin polyclonal antibody（KU）

货号: BS5880

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS5880

Product Name :Radixin polyclonal antibody（KU）

Swiss-Prot :P35241

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Ezrin, Moesin and Radixin belong to a family of highly homologous actin-associated proteins that are localized just beneath the plasma membrane. The proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share over 70% homology with Ezrin and are co-expressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Radixin polyclonal antibody detects endogenous levels of Radixin protein.

BiowMW :~ 80-90 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Contribution of ECM and Cytoskeletal Factors to EMT,

Alternative Name :RDX

Immunogen :Synthetic peptide, corresponding to amino acids 185-230 of Human Radixin.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of Radixin (W175) pAb at 1:2000 dilution Lane1:SGC7901 whole cell lysate(40ug) Lane2:L02 whole cell lysate(40ug) Lane3:The Liver tissue lysate of Rat(40ug) Lane4:The Kidney tissue lysate of Mouse(40ug)