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RAB3GAP1 polyclonal antibody

货号: BS5874

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS5874

Product Name :RAB3GAP1 polyclonal antibody

Swiss-Prot :Q15042

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Rab 3 GAP p130, also known as Rab3 GTPase-activating protein catalytic subunit, is a 981 amino acid protein that belongs to the Rab3-GAP catalytic subunit family. Rab 3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP, and is required for normal eye and brain development. Defects in Rab 3 GAP p130 are the cause of Warburg micro syndrome 1 (WARBM1). WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia. The Rab 3 GAP p130 protein may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :RAB3GAP1 polyclonal antibody detects endogenous levels of RAB3GAP1 protein.

BiowMW :~ 111 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Rab3 GTPase-activating protein catalytic subunit; RAB3 GTPase-activating protein 130 kDa subunit; Rab3-GAP p130; Rab3-GAP; KIAA0066; RAB3GAP; Rab 3 GAP p130; Rab3 GAP p130

Immunogen :Synthetic peptide, corresponding to amino acids 580-625 of Human RAB3GAP1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of RAB3GAP1 polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:sp2/0 cell lysate Lane3:PC12 cell lysate