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PSD-93 polyclonal antibody

货号: BS5868

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS5868

Product Name :PSD-93 polyclonal antibody

Swiss-Prot :Q15700

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB ICC

Application_all :WB: 1:500~1:1000 ICC: 1:50~1:200

Background :The postsynaptic density protein (PSD)-93 and related membrane associated guanylate kinase (MAGUK) proteins assemble signal transduction complexes at sites of cell-cell contact including synapses. PSD-93 (also designated channel associated protein of synapse-110 or chapsyn-110) occurs only at postsynaptic sites in hippocampal neurons. PSD-95 and PSD-93 mediate ion channel clustering in heterologous cells and are believed to cluster and anchor NMDA receptors at the synapse. The glutamate receptor subunit, delta2, binds specifically to PSD-93, which is enriched in Purkinje neuron cell bodies and dendrites. In addition, PSD-93 clusters delta2 when they are coexpressed and they are colocalized at parallel fiber synapses.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PSD-93 polyclonal antibody detects endogenous levels of PSD-93 protein.

BiowMW :~ 110 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Disks large homolog 2; Channel-associated protein of synapse-110; Chapsyn-110; Chapsyn110; Chapsyn 110; Postsynaptic density protein PSD-93; PSD93; DLG2

Immunogen :Synthetic peptide, corresponding to amino acids 647-692 of Human PSD-93.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of PSD-93 polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:NIH-3T3 cell lysate Lane3:PC12 cell lysate

Resveratrol Reverses the Synaptic Plasticity Deficits in a Chronic Cerebral Hypoperfusion Rat Model

JournalJournal of Stroke & Cerebrovascular Diseases

ApplicationWB

IF2.136

SpeciesRat

PMID26456198