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PGRMC2 polyclonal antibody

货号: BS5853

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS5853

Product Name :PGRMC2 polyclonal antibody

Swiss-Prot :O15173

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB ICC

Application_all :WB: 1:500~1:1000 ICC: 1:50~1:200

Background :PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PGRMC2 polyclonal antibody detects endogenous levels of PGRMC2 protein.

BiowMW :~ 24 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Membrane-associated progesterone receptor component 2; Progesterone membrane-binding protein; Steroid receptor protein DG6; DG6; PMBP

Immunogen :Synthetic peptide, corresponding to the 178-223 of Human PGRMC2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of PGRMC2 polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:H9C2 cell lysate Lane3:Rat brain tissue lysate