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ORC1 polyclonal antibody

货号: BS5836

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS5836

Product Name :ORC1 polyclonal antibody

Swiss-Prot :Q13415

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors. Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis. ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle; however, only ORC2 remains stably bound to chromatin. ORC4 and ORC6 are also expressed constantly throughout the cell cycle. ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble. The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ORC1 polyclonal antibody detects endogenous levels of ORC1 protein.

BiowMW :~ 97, 120 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Origin recognition complex subunit 1; Replication control protein 1; ORC1L; PARC1

Immunogen :Synthetic peptide, corresponding to amino acids 364-409 of Human ORC1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ORC1 polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:MCF-7 cell lysate Lane3:PC12 cell lysate

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）