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ZNF42 polyclonal antibody

货号: BS5810

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS5810

Product Name :ZNF42 polyclonal antibody

Swiss-Prot :P28698

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC ICC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 ICC: 1:50~1:200

Background :Zinc finger genes that encode metal-binding proteins are transcriptional regulators of other genes. Myeloid zinc finger 1 (MZF-1), also designated Zinc finger protein 42, and transcription factor ZBP-89, also designated Zinc finger protein 148, belong to the Krueppel C2H2-type zinc-finger protein family. The gene encoding for the MZF-1 protein maps to chromosome 19q13.43 while the gene encoding for ZBP-89 is localized on chromosome 3q21. These proteins are nuclear proteins involved in the regulation of transcriptional events. MZF-1 regulates transcription during hemopoietic development and plays a role in myeloid cell differentiation. MZF-1 regulates the CD34 promoter in a tissue-specific manner. MZF-1 and FHL3 can form a complex of high molecular mass with other proteins in the nucleus. It is induced by retinoic acid and is primarily expressed in differentiating myeloid cells.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ZNF42 polyclonal antibody detects endogenous levels of ZNF42 protein.

BiowMW :~ 56, 82 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Myeloid zinc finger 1; MZF-1; Zinc finger and SCAN domain-containing protein 6; Zinc finger protein 42; MZF1; MZF; ZNF42; ZSCAN6

Immunogen :Synthetic peptide, corresponding to amino acids 1-46 of Human ZNF42.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ZNF42 polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:sp2/0 cell lysate Lane3:PC12 cell lyate

Immunohistochemistry (IHC) analyzes of ZNF42 pAb in paraffin-embedded human stomach carcinoma tissue at 1:50.showing cytoplasmic and nucleus staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Transcription Factor Myeloid Zinc-Finger 1 Suppresses Human Gastric Carcinogenesis by Interacting with Metallothionein 2A

JournalClinical Cancer Research

ApplicationWB

IF8.911

SpeciesHuman

PMID30301827
Sublytic C5b‐9 induces proliferation of glomerular mesangial cells via ERK5/MZF1/RGC‐32 axis activated by FBXO28‐TRAF6 complex

JournalJournal Of Cellular And Molecular Medicine

ApplicationWB

IF4.658

SpeciesRat

PMID31184423