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MX2 polyclonal antibody

货号: BS5805

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS5805

Product Name :MX2 polyclonal antibody

Swiss-Prot :P20592

Host :Rabbit

Reactivity :Human

Applications :WB IF IP

Application_all :WB: 1:1000~1:2000 IF: 1:50~1:200 IP: 1:50~1:200

Background :Members of the Dynamin family include GTPase, microtubule-associated proteins that are involved in cellular trafficking, including microtubule bundling and endocytosis. Mx1, also known as MxA, an interferon (IFN)-induced protein, acquires a high degree of resistance to influenza A virus and the rhabdo-virus vesicular stomatitis virus (VSV), which suggests that Mx1 plays an active role against influenza virus and the rhabdovirus VSV. Mx1 is a cytoplasmic protein that is 63% identical to the Mx2 protein, which lacks antiviral activity. Mx2 is also known as MxB and is localized at the cytoplasmic face of nuclear pores. Mx2 expression is not interferon-dependent and this protein is thought to regulate the efficiency and/or kinetics of nuclear import, a function which may have been usurped by its antiviral relatives.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MX2 polyclonal antibody detects endogenous levels of MX2 protein.

BiowMW :~ 85 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding; protein MxB; Myxovirus resistance protein 2; p78-related protein

Immunogen :Recombinant full length Human MX2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of MX2 polyclonal antibody at 1:1000 dilution Lane1:A431 cell lysate(30ug) Lane2:Jurkat cell lysate(30ug) Lane3:HepG2 cell lysate(30ug) Lane4:THP-1 cell lysate(30ug)

Immunofluorescence analysis of HepG2 cells using MX2 pAb at dilution of 1:50.