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KV10.1 polyclonal antibody

货号: BS5772

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS5772

Product Name :KV10.1 polyclonal antibody

Swiss-Prot :O95259

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Voltage-gated potassium channels play an essential role in controlling cellular excitability in the nervous system. They regulate a variety of properties including membrane potential as well as the frequency and structure of action potentials. KCNH1 (potassium voltage-gated channel, subfamily H (eag-related), member 1), also known as ether-a-go-go potassium channel 1, voltage-gated potassium channel subunit Kv10.1, EAG, EAG1 or h-eag, is a 989 amino acid multi-pass membrane protein belonging to the potassium channel family and H (Eag) subfamily. KCNH1 is highly expressed in myoblasts and brain, forms two alternatively spliced isoforms and exists as a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. Encoded by a gene located on human chromosome 1, KCNH1 forms a heteromultimer with KCNH5 and also interacts with ALG10.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :KV10.1 polyclonal antibody detects endogenous levels of KV10.1 protein.

BiowMW :~ 111 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Potassium voltage-gated channel subfamily H member 1; Ether-a-go-go potassium channel 1; EAG channel 1; h-eag; hEAG1; Voltage-gated potassium channel subunit Kv10.1; KCNH1; EAG; EAG1

Immunogen :Synthetic peptide, corresponding to amino acids 762-807 of Human KV10.1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of KV10.1 polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:NIH-3T3 cell lysate Lane3:H9C2 cell lysate