Product Name :SMUG1 polyclonal antibody
Reactivity :Human,Mouse,Rat
Application_all :WB: 1:500~1:1000
IHC: 1:50~1:200
ICC: 1:50~1:200
Background :The base excision repair (BER) pathway removes incorrect bases (uracil) or damaged bases (3-methyladenine) from chromatin. Each BER enzyme system addresses a specific type of base damage. Uracil-DNA glycosylases, UNG2 and SMUG1 (single-strand selective monofunctional uracil DNA glycosylase) remove uracil from both double- and single-stranded DNA in nucleosomes (chromatin core particle). The uracil-excising enzyme family shares structural and functional conservation with minimal sequence conservation. The human SMUG1 gene maps to chromosome 12q13.13.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :SMUG1 polyclonal antibody detects endogenous levels of SMUG1 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Single-strand selective monofunctional uracil DNA glycosylase
Immunogen :Synthetic peptide, corresponding to amino acids 137-182 of Human SMUG1.
Modification :Unmodification
