Product Name :YEATS2 polyclonal antibody
Application_all :WB: 1:500~1:1000
IHC: 1:50~1:200
Background :The YEATS domain-containing protein 2 (YEATS2) is a nuclear protein that is phosphorylated upon DNA damage by ATM or ATR and contains 1 YEATS domain. The gene encoding YEATS2 resides on chromosome 3, which contains about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :YEATS2 polyclonal antibody detects endogenous levels of YEATS2 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :YEATS domain-containing protein 2; YETS2; KIAA1197
Immunogen :Synthetic peptide, corresponding to amino acids 393-438 of Human YEATS2.
Modification :Unmodification