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GAB1 (Phospho-Y659) polyclonal antibody

货号: BS5074

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS5074

Product Name :GAB1 (Phospho-Y659) polyclonal antibody

Swiss-Prot :Q13480

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB,1:500 - 1:1000

Background :The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ABCA1 polyclonal antibody detects endogenous levels of ABCA1 protein.

BiowMW :~ 254 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TGD; ABC1; CERP; ABC-1; HDLDT1; HPALP1; HDLCQTL13; ABCA1

Immunogen :Recombinant fusion protein containing a sequence corresponding to amino acids 1170-1350 of human ABCA1 (NP_005493.2).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of lysates from Mouse heart, using ABCA1 pAb at 1:1000 dilution.

Immunofluorescence analysis of NIH/3T3 cells using ABCA1 pAb at dilution of 1:100 (40x lens).

免疫沉淀（IP）

免疫组织化学（IHC）