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MRP2 Recombinant Rabbit mAb (KU)

货号: BS48479

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS48479

Product Name :MRP2 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q92887

Host :Rabbit

Reactivity :Human

Applications :WB,ICC/IF,FC

Application_all :WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100

Background :The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008]

Product :Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification&Purity :Affinity Purified

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :Calculated MW: 45 kDa; Observed MW: 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PGKA; MIG10; HEL-S-68p

Immunogen :A synthesized peptide derived from human PGK1

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of PGK1 in HepG2 lysates; mouse kidney lysates using PGK1 antibody.

免疫沉淀（IP）