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LEF-1 (phospho-S42) polyclonal antibody(KU)

货号: BS4806
价格 1350
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS4806
Product Name :LEF-1 (phospho-S42) polyclonal antibody(KU)
Swiss-Prot :Q9UJU2
Host :Rabbit
Reactivity :Human,Rat
Applications :WB
Application_all :WB: 1:500~1:1000
Background :This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :p-LEF-1 (S42) pAb detects endogenous levels of LEF-1 protein only when phosphorylated at Ser42.
BiowMW :~ 53 kDa
Note :For research use only, not for use in diagnostic procedure.
Pathway :Wntβ catenin signaling,Contribution of ECM and Cytoskeletal Factors to EMT,
Alternative Name :LEF-1; TCF10; TCF1ALPHA; TCF7L3
Immunogen :Synthetic phosphopeptide derived from human LEF-1 around the phosphorylation site of Serine 42
Conjugate :Unconjugated
Modification :Phosphorylation
Western blot (WB) analysis of p-LEF-1 (S42) pAb at 1:500 dilution Lane1:HCT116 whole cell lysate(40µg) Lane2:LOVO whole cell lysate(40µg) Lane3:DLD whole cell lysate(40µg) Lane4:The Thymus lysate of Rat(40µg)

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com