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Doublecortin Recombinant Rabbit mAb (KU)

货号: BS47266

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS47266

Product Name :Doublecortin Recombinant Rabbit mAb (KU)

Swiss-Prot :O43602

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC,ICC/IF

Application_all :WB: 1:1000<br />IHC: 1:20<br />ICC/IF: 1:50

Background :This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, cognitive disability, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain" syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :41 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DC; DBCN; LISX; SCLH; XLIS

Immunogen :Recombinant protein of human Doublecortin

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Doublecortin in Rat Brain cell using Doublecortin antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）