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ORP150 Recombinant Rabbit mAb (KU)

货号: BS47056

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS47056

Product Name :ORP150 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q9Y4L1

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC,FC

Application_all :WB: 1:1000-1:5000<br />IHC: 1:50-1:200<br />FC: 1:20

Background :The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :150 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Grp170; HSP12A; ORP150; GRP-170; ORP-150

Immunogen :A synthetic peptide of human ORP150

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of ORP150 in 293T,MCF-7 using ORP150 antibody.

免疫沉淀（IP）

免疫组织化学（IHC）