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ULK3 Recombinant Rabbit mAb (KU)

货号: BS47040

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS47040

Product Name :ULK3 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q6PHR2

Host :Rabbit

Reactivity :Human

Applications :WB, IHC, ICC/IF, FC

Application_all :WB: 1:1000-1:5000<br />IHC: 1:20-1:50<br />ICC/IF: 1:20-1:50<br />FC: 1:20

Background :Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :53 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Unc-51-like kinase 3

Immunogen :A synthetic peptide of human ULK3

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of ULK3 in K562,Hela cell lysates using ULK3 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）