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RASGRF1 Recombinant Rabbit mAb (KU)

货号: BS46974

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46974

Product Name :RASGRF1 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q13972

Host :Rabbit

Reactivity :Human, Rat

Applications :WB

Application_all :WB: 1:1000-1:5000

Background :The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :145 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GNRP; GRF1; CDC25; GRF55; CDC25L; H-GRF55; PP13187; ras-GRF1

Immunogen :A synthetic peptide of human RASGRF1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of CDC25 in Rat Brain lysates using CDC25 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）