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Ionotropic Glutamate Receptor 2 Recombinant Rabbit mAb (KU)

货号: BS46955

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :BS46955

Product Name :Ionotropic Glutamate Receptor 2 Recombinant Rabbit mAb (KU)

Swiss-Prot :P42262

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,ICC/IF,FC

Application_all :WB: 1:1000-1:10000<br />ICC/IF: 1:50<br />FC: 1:50

Background :Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :99 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GLUR2; GLURB; GluA2; HBGR2; GluR-K2

Immunogen :A synthetic peptide of human Ionotropic Glutamate receptor 2

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Ionotropic Glutamate receptor 2 in C6 cell lysates using Ionotropic Glutamate receptor 2 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）