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Stromal Interaction Molecule 1 Recombinant Rabbit mAb (KU)

货号: BS46943

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :BS46943

Product Name :Stromal Interaction Molecule 1 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q13586

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IP

Application_all :WB: 1:1000-1:5000<br />IHC: 1:20-1:50<br />IP: 1:20-1:50

Background :This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :77 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GOK; TAM; TAM1; IMD10; STRMK; D11S4896E

Immunogen :A synthetic peptide of human Stromal interaction molecule 1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Stromal interaction molecule 1 in MCF7,C6,3T3,Hela cell lysates using Stromal interaction molecule 1 antibody(1:1000 diluted).