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KRIT1 Recombinant Rabbit mAb (KU)

货号: BS46933

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :BS46933

Product Name :KRIT1 Recombinant Rabbit mAb (KU)

Swiss-Prot :O00522

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB,IHC,ICC/IF

Application_all :WB: 1:1000<br />IHC: 1:20<br />ICC/IF: 1:20

Background :This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :84 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CAM; CCM1

Immunogen :Recombinant protein of human KRIT1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of KRIT1 in C6,3T3,Hela,K562 cell lysates using KRIT1 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）