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KCTD21 Recombinant Rabbit mAb (KU)

货号: BS46925

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46925

Product Name :KCTD21 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q4G0X4

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,FC

Application_all :WB: 1:1000<br />FC: 1:50

Background :Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142).

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :30 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KCASH2

Immunogen :Recombinant protein of human KCTD21

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of KCTD21 in K562 cell lysates using KCTD21 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）