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Metabotropic Glutamate Receptor 2 Recombinant Rabbit mAb (KU)

货号: BS46901

价格：￥ 1200

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS46901

Product Name :Metabotropic Glutamate Receptor 2 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q14416

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, ICC/IF, FC

Application_all :WB: 1:2000-1:10000<br />IHC: 1:50<br />ICC/IF: 1:50<br />FC: 1:20

Background :L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :99 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GLUR2; mGlu2; GPRC1B; MGLUR2

Immunogen :A synthetic peptide of human Metabotropic Glutamate Receptor 2

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Metabotropic Glutamate Receptor 2 in K562,Hela cell lysates using Metabotropic Glutamate Receptor 2 antibody(1:1000 diluted).