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SynGAP Recombinant Rabbit mAb (KU)

货号: BS46877

价格：￥ 1200

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS46877

Product Name :SynGAP Recombinant Rabbit mAb (KU)

Swiss-Prot :Q96PV0

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, ICC/IF, FC

Application_all :WB: 1:1000-1:2000<br />ICC/IF: 1:20<br />FC: 1:20

Background :This gene encodes a Ras GTPase activating protein that is a member of the N-methyl-D-aspartate receptor complex. The N-terminal domain of the protein contains a Ras-GAP domain, a pleckstrin homology domain, and a C2 domain that may be involved in binding of calcium and phospholipids. The C-terminal domain consists of a ten histidine repeat region, serine and tyrosine phosphorylation sites, and a T/SXV motif required for postsynaptic scaffold protein interaction. The encoded protein negatively regulates Ras, Rap and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking to the postsynaptic membrane to regulate synaptic plasticity and neuronal homeostasis. Allelic variants of this gene are associated with intellectual disability and autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :148 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MRD5; RASA1; RASA5; SYNGAP

Immunogen :A synthetic peptide of human SynGAP

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of SynGAP in Rat Brain cell using SynGAP antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）